In the vibrant city of New Orleans, a team of criminal investigators from the Naval Criminal Investigative Service (NCIS) works to solve crimes involving military personnel. Led by the charismatic and driven Supervisory Special Agent Dwayne Cassius Pride, the team includes a diverse range of experts, from a former Jefferson Parish Sheriff's Deputy to a transfer from the NCIS Great Lakes field office. With the help of a colorful coroner and a skilled forensics specialist, the team investigates cases that span from Pensacola to Texas, uncovering dark secrets in the process. As they navigate their way through complex mysteries and dangerous missions, these agents must also contend with their own personal demons and conflicts.

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