Meet Nate Wright, a charismatic and mischievous 11-year-old who's always up for an adventure. Along with his best friends Francis and Teddy, Nate navigates the ups and downs of sixth grade, from detention at school to disasters at home. But no matter the challenge, Nate never loses his spirit. With a vivid imagination and a talent for drawing, he expresses himself through cartoons that bring his misadventures to life. Join Nate and his friends on their hilarious escapades as they prove that even the most unlikely heroes can be big-time fun.

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Some TV shows that have similar genres and were produced around the same time as Big Nate include SpongeBob SquarePants, Marcus Level, Alf Tales, We Bare Bears, The Tom and Jerry Show, Pokémon Master Journeys.