Two American students, David and Jack, embark on a hiking trip in rural England. One night,; they are attacked by a mysterious creature that kills Jack and injures David. David wakes up in a hospital three weeks later with no memory of the attack. His friend Jack appears to him as an undead spirit and warns him that they were attacked by a werewolf; since David was bitten , he will transform into a werewwolf during the next full moon. Jack urges David to kill himself to prevent harming others. David is skeptical, but upon his release from the hospital, Jack appears to him again, decaying more and more each time, urging him to take his own life. David transforms into a werewolf during the next full moon ad goes on a killing spree in London before waking up naked in a wolf enclosure at the London Zoo with no memory of the night's events. Desperate to end his curse , David attempts suicide but is interrupted by Jack, who introduces him to his previous night's victims trapped in limbo like him. The victims suggest ways for David to kill himself and free them, but David transforms into a werewolf again and goes on another killing spree before being trapped by the police and shot dead by a silver bullet.

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