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IMDb rating 6.3
Critic rating Average critic rating
Critic rating 8

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Critic William Thomas
rated 8

Kids, with their propensity for giggling at anything bodily functions-related, will have a field day.

Read full review at Empire

Cast & Crew

Ron Howard
As Tom Colonic (voice)
Ron Howard
Director
Peter Farrelly
Director
Bobby Farrelly
Director
William Shatner
As Mayor Phlegmming (voice)
Molly Shannon
As Mrs. Boyd
Chris Rock
As Osmosis Jones (voice)

Frequently Asked Questions

What is Osmosis Jones about? Toggle content

In "Osmosis Jones," a policeman white blood cell and a cold pill team up to save their human host, Frank, from a deadly virus that threatens to destroy his body. With the help of his partner, Drix, Osmosis Jones must stop the virus Thrax and his gang of sweat germs before they cause irreparable damage to Frank's health. But as they fight to protect Frank's body, Ozzy and Drix discover that their differences may be their greatest strength. Can this unlikely duo put aside their disagreements and save Frank before it's too late?

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When was Osmosis Jones released in theaters? Toggle content

Osmosis Jones was released in theaters on August 10, 2001.