In the fourth installment of the Scream franchise, Sidney Prescott, a successful self-help author, returns to her hometown of Woodsboro for a book tour. Her arrival coincides with the 15th anniversary of the original Woodsboro murders, and soon after, high school students Jenny Randall and Marnie Cooper are killed by Ghostface. As evidence is found in Sidney's rental car, she becomes a prime suspect and must stay in town until the murders are solved. Sidney's cousin Jill Roberts and her friends receive threatening phone calls from Ghostface. When Olivia Morris is killed by Ghostface in front of Jill and Kirby Reed, Sidney is forced to face her past traumas again. As more people close to Sidney are targeted by Ghostface, including Jill's ex-boyfriend Trevor Sheldon, Gale Weathers investigates against her husband Dewey Riley's wishes. In an intense confrontation between Sidney and Ghostface at Jill's house, Rebecca Walters is killed by Ghostface moments after being fired by Sidney for attempting to exploit the situation for publicity gain. As more bodies pile up - including that of Dewey himself - it becomes clear that this time around there is more than one killer on the loose as perennial survivor Sydney Prescott fights once again to stay alive while uncovering dark secrets lurking beneath Woodsboro's seemingly idyllic façade... with some surprising revelations that will leave viewers guessing until very end!

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Some movies that have similar genres and were produced around the same time as Scream 4 include Last Shift, Case 39, The Skin I Live In, The Invasion, The Poughkeepsie Tapes, The Autopsy of Jane Doe.

Scream 4 was released in theaters on April 15, 2011.