My B.F.F. is a heartwarming drama that follows the unbreakable bond between two best friends, Gemma and Marni, who have been inseparable since they were babies. Shot on location in New Orleans, the film takes a poignant look at the girls' journey as they navigate the challenges of growing up and confronting issues of race, identity, and politics. When Marni's mother passes away, she is left with a deep void, but her friendship with Gemma and her family helps her find solace. Years later, the girls have the opportunity to apply to a prestigious magnet school for the arts, but when Marni's father misses the registration deadline, Gemma convinces her to take matters into their own hands. The film takes an unexpected turn as the girls learn valuable lessons about friendship, family, and growing up in a world that is not always fair or just.

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Some movies that have similar genres and were produced around the same time as My B.F.F. include Heritage Falls, The Young and Prodigious T.S. Spivet, Wonder, Geek Charming, Touchback, Cloud 9.